Signs
and Symptoms of Cancer
What
are signs and symptoms?
Signs and symptoms are
both signals of injury, illness, disease – signals that something is not right
in the body.
A sign is a signal that can be
seen by someone else – maybe a loved one, or a doctor, nurse, or other health
care professional. For example, fever, fast breathing, and abnormal lung sounds
heard through a stethoscope may be signs of pneumonia.
A symptom is a signal that’s
felt or noticed by the person who has it, but may not be easily seen by anyone
else. For example, weakness, aching, and feeling short of breath may be
symptoms of pneumonia.
Having one sign or symptom may not be enough to figure out
what’s causing it. For example, a rash in a child could be a sign of a number
of things, such as poison ivy, measles, a skin infection, or a food allergy.
But if the child has the rash along with other signs and symptoms like a high
fever, chills, achiness, and a sore throat, then a doctor can get a better
picture of the illness. Sometimes, a patient’s signs and symptoms still don’t
give the doctor enough clues to be sure what’s causing the illness. Then medical tests, such as x-rays, blood tests, or a biopsy may be
needed.
How
does cancer cause signs and symptoms?
Cancer is a group of diseases that can cause almost any sign or
symptom. The signs and symptoms will depend on where the cancer is, how big it
is, and how much it affects the organs or tissues. If a cancer has spread (metastasized), signs or symptoms may appear in
different parts of the body.
As a cancer grows, it
can begin to push on nearby organs, blood vessels, and nerves. This pressure
causes some of the signs and symptoms of cancer. If the cancer is in a critical
area, such as certain parts of the brain, even the smallest tumor can cause
symptoms.
But sometimes cancer starts in places where it won’t cause any
signs or symptoms until it has grown quite large. Cancers of the pancreas, for
example, usually don’t cause symptoms until they grow large enough to press on
nearby nerves or organs (this causes back or belly pain). Others may grow
around the bile duct and block the flow of bile. This causes the eyes and skin
to look yellow (jaundice). By the time a pancreatic
cancer causes signs or symptoms like these, it’s usually in an advanced stage.
This means it has grown and spread beyond the place it started – the pancreas.
A cancer may also cause symptoms like fever, extreme tiredness (fatigue), or weight loss. This may be because cancer
cells use up much of the body’s energy supply, or they may release substances
that change the way the body makes energy from food. Cancer can also cause the
immune system to react in ways that produce these signs and symptoms.
Sometimes, cancer
cells release substances into the bloodstream that cause symptoms that are not
usually linked to cancer. For example, some cancers of the pancreas can release
substances that cause blood clots in veins of the legs. Some lung cancers make
hormone-like substances that raise blood calcium levels. This affects nerves
and muscles, making the person feel weak and dizzy.
How
are signs and symptoms helpful?
Treatment works best
when cancer is found early – while it’s still small and is less likely to have
spread to other parts of the body. This often means a better chance for a cure,
especially if the cancer can be removed with surgery.
A good example of the importance of finding cancer early is
melanoma skin cancer. It can be easy to remove if it has not grown deep into
the skin. The 5-year survival rate (percentage
of people who live at least 5 years after diagnosis) at this early stage is
around 98%. Once melanoma has spread to other parts of the body, the 5-year
survival rate drops to about 16%.
Sometimes people
ignore symptoms. Maybe they don’t know that the symptoms could mean something
is wrong. Or they might be frightened by what the symptoms could mean and don’t
want to get medical help. Maybe they just can’t afford to get medical care.
Some symptoms, such as
tiredness or coughing, are more likely caused by something other than cancer.
Symptoms can seem unimportant, especially if there’s a clear cause or the
problem only lasts a short time. In the same way, a person may reason that a
symptom like a breast lump is probably a cyst that will go away by itself. But
no symptom should be ignored or overlooked, especially if it has lasted a long
time or is getting worse.
Most likely, symptoms
are not caused by cancer, but it’s important to have them checked out, just in
case. If cancer is not the cause, a doctor can help figure out what the cause
is and treat it, if needed.
Sometimes, it’s possible to find cancer before having symptoms.
The American Cancer Society and other health groups recommend cancer-related
check-ups and certain tests for people even though they have no symptoms. This
helps find certain cancers early, before symptoms start. For more information
on early detection tests, see our document called American Cancer Society Guidelines for the Early Detection of Cancer.
But keep in mind, even if you have these recommended tests, it’s still
important to see a doctor if you have any symptoms.
What
are some general signs and symptoms of cancer?
You should know some
of the general signs and symptoms of cancer. But remember, having any of these
does not mean that you have cancer – many other things cause these signs and
symptoms, too. If you have any of these symptoms and they last for a long time
or get worse, please see a doctor to find out what’s going on.
Unexplained weight loss
Most people with cancer will lose weight at some point. When you
lose weight for no known reason, it’s called anunexplained weight loss.
An unexplained weight loss of 10 pounds or more may be the first sign of
cancer. This happens most often with cancers of the pancreas, stomach, esophagus (swallowing
tube), or lung.
Fever
Fever is very common with cancer, but it more often happens
after cancer has spread from where it started. Almost all people with cancer
will have fever at some time, especially if the cancer or its treatment affects
the immune system. (This can make it harder for the body to fight infection.)
Less often, fever may be an early sign of cancer, such as blood cancers like leukemia or lymphoma.
Fatigue
Fatigue is extreme tiredness that doesn’t get better with rest.
It may be an important symptom as cancer grows. But it may happen early in some
cancers, like leukemia. Some colon or stomach cancers
can cause blood loss that’s not obvious. This is another way cancer can cause
fatigue.
Pain
Pain may be an early symptom with some cancers like bone cancers or testicular cancer.
A headache that does not go away or get better with treatment may be a symptom
of a brain tumor. Back pain can be a symptom of cancer of the colon, rectum,
or ovary. Most
often, pain due to cancer means it has already spread (metastasized) from where
it started.
Skin changes
Along with skin cancers,
some other cancers can cause skin changes that can be seen. These signs and
symptoms include:
·
Darker looking skin (hyperpigmentation)
·
Yellowish skin and eyes (jaundice)
·
Reddened skin (erythema)
·
Itching (pruritis)
·
Excessive hair growth
Signs
and symptoms of certain cancers
Along with the general
symptoms, you should watch for certain other common signs and symptoms that
could suggest cancer. Again, there may be other causes for each of these, but
it’s important to see a doctor about them as soon as possible – especially if there’s
no other cause you can identify, the problem lasts a long time, or it gets
worse over time.
Change in bowel habits or bladder function
Long-term constipation, diarrhea, or a change in the size of the
stool may be a sign of colon cancer.
Pain when passing urine, blood in the urine, or a change in bladder function
(such as needing to pass urine more or less often than usual) could be related
to bladder or prostate cancer.
Report any changes in bladder or bowel function to a doctor.
Sores that do not heal
Skin cancers may bleed and look like sores that don’t
heal. A long-lasting sore in the mouth could be an oral cancer. This should be dealt with right away, especially
in people who smoke, chew tobacco, or often drink alcohol. Sores on the penis
or vagina may either be signs of infection or an early cancer, and should be
seen by a health professional.
White patches inside the mouth or white spots on the tongue
White patches inside the mouth and white spots on the tongue may
be leukoplakia. Leukoplakia is a pre-cancerous area that’s
caused by frequent irritation. It’s often caused by smoking or other tobacco
use. People who smoke pipes or use oral or spit tobacco are at high risk for
leukoplakia. If it’s not treated, leukoplakia can become mouth cancer. Any long-lasting mouth changes should be checked
by a doctor or dentist right away.
Unusual bleeding or discharge
Unusual bleeding can happen in early or advanced cancer.
Coughing up blood may be a sign of lung cancer.
Blood in the stool (which can look like very dark or black stool) could be a
sign of colon or rectal cancer. Cancer of the cervixor the endometrium (lining
of the uterus) can cause abnormal vaginal bleeding. Blood in the urine may be a
sign ofbladder or kidney cancer.
A bloody discharge from the nipple may be a sign of breast cancer.
Thickening or lump in the breast or other parts of the body
Many cancers can be felt through the skin. These cancers occur
mostly in the breast, testicle,
lymph nodes (glands), and the soft tissues of the body. A lump or thickening
may be an early or late sign of cancer and should be reported to a doctor,
especially if you’ve just found it or notice it has grown in size. Keep in mind
that some breast cancers show up as red or thickened skin rather than a lump.
Indigestion or trouble swallowing
Indigestion or swallowing problems that don’t go away may be
signs of cancer of the esophagus (the
swallowing tube that goes to the stomach), stomach, or pharynx (throat). But like most symptoms on this
list, they are most often caused by something other than cancer.
Recent change in a wart or mole or any new skin change
Any wart, mole, or freckle that changes color, size, or shape,
or that loses its sharp border should be seen by a doctor right away. Any other
skin changes should be reported, too. A skin change may be a melanoma which,
if found early, can be treated successfully. See pictures of skin cancers and
other skin conditions in our Skin Cancer Image Gallery.
Nagging cough or hoarseness
A cough that does not go away may be a sign of lung cancer.
Hoarseness can be a sign of cancer of the larynx(voice box) or thyroid gland.
Other symptoms
The signs and symptoms
listed above are the more common ones seen with cancer, but there are many
others that are not listed here. If you notice any major changes in the way
your body works or the way you feel – especially if it lasts for a long time or
gets worse – let a doctor know. If it has nothing to do with cancer, the doctor
can find out more about what’s going on and, if needed, treat it. If it is
cancer, you’ll give yourself the chance to have it treated early, when
treatment works best.
